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Parathyroidhormone (1-34) (rat) (acetate) is a parathyroidhormone. Parathyroidhormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroidhormone (1-34) (rat) can be used for the research of osteoporosis .
ParathyroidHormone (1-34), bovine is a potent parathyroidhormone (PTH) receptor agonist. ParathyroidHormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. ParathyroidHormone (1-34), bovine can be used for th reseach of osteoporosis .
ParathyroidHormone (1-34), human, biotinylated is a probe for the parathyroidhormone receptor, can be used for analyzing the interaction between parathyroidhormone and parathyroidhormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .
Parathyroidhormone (1-34) (rat) is a parathyroidhormone. Parathyroidhormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroidhormone (1-34) (rat) can be used for the research of osteoporosis .
ParathyroidHormone (1-34), bovine TFA is a potent parathyroidhormone (PTH) receptor agonist. ParathyroidHormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. ParathyroidHormone (1-34), bovine can be used for th reseach of osteoporosis .
Teriparatide acetate hydrate (Human parathyroidhormone-(1-34) acetate hydrate) is a PTH1 receptor agonist. Teriparatide acetate hydrate (Human parathyroidhormone-(1-34) acetate hydrate) can be used for osteoporosis research .
Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia .
Glutaurine (Litoralon) TFA containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine (Litoralon) TFA, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine (Litoralon) TFA can be used for the research of antiepileptic and anti-amnesia .
Ronacaleret (SB 751689) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroidhormone release from the parathyroid glands. Ronacaleret (SB 751689) is used for the study of postmenopausal osteoporosis .
Ronacaleret hydrochloride (SB 751689A) is an orally active, potent, and selective calcium-sensing receptor (CaSR) antagonist that stimulates endogenous parathyroidhormone release from the parathyroid glands. Ronacaleret hydrochloride (SB 751689A) is used for the study of postmenopausal osteoporosis .
Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroidhormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
DPC-AJ1951, a 14 amino acid peptide that acts as a potent agonist of the parathyroidhormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 in ex vivo and in vivo assays of bone resorption .
DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroidhormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption .
Upacicalcet sodium is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroidhormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT) .
Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroidhormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT) .
(Rac)-Upacicalcet is the racemate of Upacicalcet.Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroidhormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT) .
DS69910557 is a potent, selective and orally activehuman parathyroidhormone receptor 1 (hPTHR1) antagonist. DS69910557 has antagonistic activity for PTHR1 with an IC50 value of 0.08 μM. DS69910557 can be used for the research of hyperparathyroidism, hypercalcemia of malignancy and osteoporosis .
TIP 39, Tuberoinfundibular Neuropeptide is a neuropeptide and parathyroidhormone 2 receptor (PTH2R) agonist. TIP 39 is highly conserved among species. TIP39 from all species activates adenylyl cyclase and elevates intracellular calcium levels through parathyroidhormone 2 receptor (PTH2R) .
Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroidhormone in the body) .
Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroidhormone) associated with chronic renal failure.
Osteostatin (human), a fragment of parathyroidhormone-related protein (PTHrP) 107-139, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis .
Paricalcitol-d6 is the deuterium labeled Paricalcitol. Paricalcitol is a agent used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroidhormone) associated with chronic renal failure[1].
Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroidhormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis .
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroidhormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis .
Tigapotide (PCK-3145) is an anti-tumour peptide that reduces the development of skeletal metastases associated with prostate cancer. Tigapotide induces apoptosis and reduces tumour parathyroidhormone-related peptide (PTHrP) levels .
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroidhormone-related protein fragment that can inhibit bone resorption .
Paricalcitol (Standard) is the analytical standard of Paricalcitol. This product is intended for research and analytical applications. Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroidhormone) associated with chronic renal failure.
Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroidhormone-related protein .
SB-423557 is an orally active calcium-sensing receptor (CaR) antagonist (IC50=520 nM), precursor of SB-423562 (IC50=73 nM). SB-423557 is well tolerated in human and increases plasma concentrations of exogenous parathyroidhormone (PTH) and stimulates bone formation .
Abaloparatide (BA 058) is a parathyroidhormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis .
Osteostatin, a fragment of parathyroidhormone-related protein (PTHrP) 107-111, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis, inhibits collagen-induced arthritis and inhibits osteoclastic bone resorption directly. Osteostatin can be used for inflammation and immunology research .
Abaloparatide TFA (BA 058 TFA) is a parathyroidhormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .
AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC50 value of 0.82 μM. AH3960 also serves as an agonist of parathyroidhormone receptor-1 (PTHR1) .
pTH (1-37) (human) is a fragment of parathyroidhormone (PTH). pTH (1-37) (human) induces the cAMP formation and increases alkaline phosphatase activity. pTH (1-37) (human) increases growth, bone calcium content, and bone mineral density (BMD) in uremic animals. pTH (1-37) (human) has the potential for the research of osteoporosis .
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroidhormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation .
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroidhormone secretion .
Parathyroidhormone (1-34) (rat) (acetate) is a parathyroidhormone. Parathyroidhormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroidhormone (1-34) (rat) can be used for the research of osteoporosis .
ParathyroidHormone (1-34), bovine is a potent parathyroidhormone (PTH) receptor agonist. ParathyroidHormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. ParathyroidHormone (1-34), bovine can be used for th reseach of osteoporosis .
ParathyroidHormone (1-34), human, biotinylated is a probe for the parathyroidhormone receptor, can be used for analyzing the interaction between parathyroidhormone and parathyroidhormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .
Parathyroidhormone (1-34) (rat) is a parathyroidhormone. Parathyroidhormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroidhormone (1-34) (rat) can be used for the research of osteoporosis .
ParathyroidHormone (1-34), bovine TFA is a potent parathyroidhormone (PTH) receptor agonist. ParathyroidHormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. ParathyroidHormone (1-34), bovine can be used for th reseach of osteoporosis .
Teriparatide (Human parathyroidhormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroidhormone-(1-34)) can be used for osteoporosis research .
DPC-AJ1951, a 14 amino acid peptide that acts as a potent agonist of the parathyroidhormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 in ex vivo and in vivo assays of bone resorption .
DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroidhormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption .
TIP 39, Tuberoinfundibular Neuropeptide is a neuropeptide and parathyroidhormone 2 receptor (PTH2R) agonist. TIP 39 is highly conserved among species. TIP39 from all species activates adenylyl cyclase and elevates intracellular calcium levels through parathyroidhormone 2 receptor (PTH2R) .
Osteostatin (human), a fragment of parathyroidhormone-related protein (PTHrP) 107-139, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis .
Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroidhormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis .
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroidhormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis .
Tigapotide (PCK-3145) is an anti-tumour peptide that reduces the development of skeletal metastases associated with prostate cancer. Tigapotide induces apoptosis and reduces tumour parathyroidhormone-related peptide (PTHrP) levels .
pTH-Related Protein (1-37) (human, mouse, rat), the peptide analogue of pTH-Related Protein (pTHrP). pTHrP refers to parathyroid-hormone-related protein, involved in physiological regulation of bone formation .
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroidhormone-related protein fragment that can inhibit bone resorption .
Abaloparatide (BA 058) is a parathyroidhormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis .
Osteostatin, a fragment of parathyroidhormone-related protein (PTHrP) 107-111, promotes bone repair in animal models of bone defects and prevents bone erosion in inflammatory arthritis, inhibits collagen-induced arthritis and inhibits osteoclastic bone resorption directly. Osteostatin can be used for inflammation and immunology research .
Abaloparatide TFA (BA 058 TFA) is a parathyroidhormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .
pTH (1-37) (human) is a fragment of parathyroidhormone (PTH). pTH (1-37) (human) induces the cAMP formation and increases alkaline phosphatase activity. pTH (1-37) (human) increases growth, bone calcium content, and bone mineral density (BMD) in uremic animals. pTH (1-37) (human) has the potential for the research of osteoporosis .
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) is a potent and competitive antagonist of parathyroidhormone (PTH), with a Ki of 69 nM in bovine renal cortical membrane. (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) can be used for growth and development regulation .
Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroidhormone-related protein .
PTH Protein, or parathyroid hormone, raises calcium levels by dissolving bone salts and inhibiting kidney excretion. It also stimulates [1-14C]-2-deoxy-D-glucose transport and glycogen synthesis in osteoblastic cells, interacting with the PTH1R receptor and binding to its N-terminal extracellular domain for these effects. PTH Protein, Human (HEK293, His) is the recombinant human-derived PTH protein, expressed by HEK293 , with N-8*His labeled tag. The total length of PTH Protein, Human (HEK293, His) is 84 a.a., with molecular weight of ~15 kDa.
PTH1R Protein, Human (HEK 293, His) is a recombinant PTH1R protein with a His-Flag. PTH1R plays an important role in skeletal development and homeostasis.
PTH Protein, or parathyroid hormone, raises calcium levels by dissolving bone salts and inhibiting kidney excretion. It also stimulates [1-14C]-2-deoxy-D-glucose transport and glycogen synthesis in osteoblastic cells, interacting with the PTH1R receptor and binding to its N-terminal extracellular domain for these effects. PTH Protein, Human (GST) is the recombinant human-derived PTH protein, expressed by E. coli , with N-GST labeled tag. The total length of PTH Protein, Human (GST) is 34 a.a., with molecular weight of ~30 kDa.
The PTHrP protein is a key neuroendocrine peptide that regulates multiple cellular processes, including growth, development, migration, differentiation, and survival. It plays an integral role in epithelial calcium transport and key developmental events such as endochondral bone development, mammary gland, and tooth formation. PTHrP Protein, Human (His) is the recombinant human-derived PTHrP protein, expressed by E. coli , with N-6*His labeled tag. The total length of PTHrP Protein, Human (His) is 139 a.a., with molecular weight of 19.7 kDa.
Paricalcitol-d6 is the deuterium labeled Paricalcitol. Paricalcitol is a agent used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroidhormone) associated with chronic renal failure[1].